Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Data on the aquatic toxicity of the target substance Fatty acids, C18-unsaturated, 1,6 Hexanediol Diester (EC 947-912-3) are not available. Therefore, the aquatic toxicity of the target substance was assessed by means of a read-across approach, through which additional data from a structurally and chemically closely related source substance was compiled in order to fulfil the standard information requirements laid down in Annex XI of REACh Regulation (EC) No 1907/2006. Read-across was performed in accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5.

The target substance will be assessed on the basis of aquatic toxicity data compiled from the source substances Hexanedioic acid, di-C16-18 alkyl esters (CAS 92969-90-9) and Bis(tridecyl) adipate (CAS 16958-92-2). The source substances were selected on the basis of structural similarities and similarities in properties and/or activities to the target substance, with due regard of the requirements for adequacy and reliability of data. Based on the similarity between the structural and physico-chemical properties of the target and the source substances, it is assumed that the target substance will have a similar ecotoxicological profile as the selected source substances. A detailed read-across justification is provided in IUCLID section 13.

The available short-term and long-term toxicity studies on the source substances determined no acute or chronic effects of the source substances within the limits of water solubility. Detrimental effects on aquatic microorganisms were not observed in the available read-across study.

Therefore, it can be concluded that the target substance Fatty acids, C18-unsaturated, 1,6 Hexanediol Diester (EC 947-912-3) will not be acutely or chronically toxic to aquatic organisms within the limits of water solubility. Detrimental effects on microorganisms are not expected.