Amines, C12-16 alkyl dimethyl, reaction products with ethyl chloroacetate, 2-(2-aminoethylamino)ethanol and 2-propenoic acid

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.918 µg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

9.18 µg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.092 µg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

5 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

56 µg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

5.6 µg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

4.48 µg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

PNEC_{aqua (freshwater)}

Three acute studies with the freshwater organisms fish, Daphnia and alga are available for the test item, but no long-term or reproduction study. Therefore, in accordance with the Guidance on Information requirements and chemical safety assessment, R.10, an assessment factor of 1000 was applied and the PNEC_{aqua (freshwater)} was derived from the 72 h EC50 value of 0.918 mg/L, determined with Desmodesmus subspicatus, the most sensitive of the organisms tested.This results in a PNEC_{aqua (freshwater)}of 0.918 µg/L.

PNEC_{aqua (marine water)}

Three acute studies with the freshwater organisms fish, Daphnia and alga are available for the test item, but no long-term or reproduction study. Therefore, in accordance with the Guidance on Information requirements and chemical safety assessment, R.10, an assessment factor of 10000 was applied and the PNEC aqua (freshwater) was derived from the 72 h EC50 value of 0.918 mg/L, determined with Desmodesmus subspicatus, the most sensitive of the organisms tested. This results in a PNEC_{aqua (marine water)} of 0.0918 µg/L.

PNEC_{aqua(Intermittent release)}

Acute tests with fish, aquatic invertebrates and algae are available. In accordance with the Guidance in Information requirements and chemical safety assessment, R.10, an assessment factor of 100 was applied to the lowest L(E)C50, which was the 72 h LC50 in Desmodesmus subspicatus of 0.918 mg/L. Thus, the PNEC_{aqua(Intermittent release)}was calculated to be 9.18 µg/L.

 

PNEC_STP

The PNEC_STPwas based on the 3 h EC₁₀ of > 50 mg/L obtained in a respiration inhibition test with activated sludge. Based on the available data, an assessment factor of 10 was applied in accordance with the Guidance in Information requirements and chemical safety assessment, R.10, to calculate the PNEC_STP = 5 mg/L.

Conclusion on classification

The lowest acute toxicity value is the 72 h EC50 to Desmodesmus subspicatus of 0.918 mg/L. The 72 h algae NOEC value is 0.225 mg/L.

Based on these results, the substance is classified as Aquatic acute 1 with H410 Very toxic to aquatic life with long lasting effects with regard to acute effects and as Aquatic chronic 3 with H412 Harmful to aquatic life with long lasting effects with regard to chronic effects according to Regulation EC No 1272/2008.

According to Directive 67/548/EEC the substance is classified as Dangerous for the environment with R50 Very toxic to aquatic organisms.