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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
November 17, 2016 - June 23, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.8 (Partition Coefficient - HPLC Method)
Deviations:
no
GLP compliance:
no
Remarks:
The test laboratory is GLP-certified.
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
2.54
Temp.:
20 °C
pH:
7.5
Conclusions:
The partition coefficient at 20 °C of the test item Thiocure® TEMPIC was determined by means of the HPLC method, according to Regulation EC No. 440/2008 method A.8. and OECD Test Guideline 117 (2004) to be:
log POW = 2.54 ± < 0.01


Executive summary:

The partition coefficient at 20 °C of the test item Thiocure® TEMPIC was determined by means of the HPLC method, according to Regulation EC No. 440/2008 method A.8. and OECD Test Guideline 117 (2004) to be:

log POW= 2.54 ± < 0.01

Description of key information

Key value for chemical safety assessment

Log Kow (Log Pow):
2.54
at the temperature of:
20 °C

Additional information