1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic acid

PBT assessment

Assessed Substance

Assessed substance:

substance itself

Reference

Reference substance name:

Unnamed

IUPAC name:

nonafluorobutane-1-sulfonic acid

Inventory number:

InventoryMultipleMappingImpl [inventoryEntryValue=EC 206-793-1]

CAS number:

375-73-5

Identity:

1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulphonic_acid

Identity:

1-Butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonafluoro-

Identity:

1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonic acid

Molecular formula:

C4HF9O3S

Molecular weight:

300.1

SMILES notation:

OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChl:

InChI=1/C4HF9O3S/c5-1(6,3(9,10)11)2(7,8)4(12,13)17(14,15)16/h(H,14,15,16)

Reference

Name:

PFBS pure

Type of composition:

legal entity composition of the substance

State / form:

liquid

Reference substance:

PFBS pure

PBT status of the assessed substance:

the substance is not PBT / vPvB

Results of detailed PBT / vPvB assessment

Persistence

Evidence of non-P / non-vP properties

Screening criteria

Criteria based on Annex XIII of REACH

Further information for the PBT assessment is necessary

Remark:

PFBS is not expected to biodegrade or to undergo hydrolysis or photolysis. The substance is not readily biodegradable.

Conclusion

Conclusion on P / vP properties:

vP (and P)

Bioaccumulation

Evidence of non-B / non-vB properties

Screening criteria

Not B and not vB based on: Log Kow ≤ 4.5

Remark:

The substance shows a high water solubility of 50g/L

Criteria based on Annex XIII of REACH

Further information for the PBT assessment is necessary

Remark:

Bioaccumulation of PFBS has been studied and a number of reports are available in literature. Bioconcentration factors ranging from 0.30 to 1.44 have been reported, well below the REACH criteria of 2000 for B and 5000 for vB, respectively.

Conclusion

Conclusion on B / vB properties:

not B/vB

Toxicity

Evidence of non-T properties

Criteria based on Annex XIII of REACH

Not T based on:

EC10 or NOEC ≥ 0.01 mg/L for marine / freshwater organisms (long-term toxicity):

The 48-hour EC50 of PFBSK+ to Daphnia magna was examined in a static test conducted according to EPA 850.1010 and OECD TG 202. 20% cumulative immobilization was observed at 1707 mg/L, and 100% cumulative immobilization was observed at 9433 mg/L. The 48-hour EC50 was determined as 2183 mg/L.
Additional studies are available for long term aquatic and terrestric toxicity of PFBS, which show that NOEC values are well above the toxicity threshold of 0.01 mg/L.

and substance is not classified as carcinogenic (category 1 or 2), mutagenic (category 1 or 2), or toxic for reproduction (category 1, 2 or 3) according to Directive 67/548/EEC or carcinogenic (category 1A or 1B), germ cell mutagenic (category 1A or 1B), or toxic for reproduction (category 1A, 1B or 2) according to Regulation EC No 1272/2008:

Sufficient long term data data are available for the source substance PFBSK+ which indicate that it is not to be classified as CMR Cat 1 or 2. Read across of this property to the target substance PFBS is valid for long term endpoints.

Other evidence of non-T properties

Remark:

2-hour EC50 of PFBSK+ to Pseudokirchneriella subcapitata was 5661 mg a.i./L

Evidence of T properties

Conclusion

Conclusion on T properties:

not T