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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms, other
- Remarks:
- toxicity control of biodegradation test
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- 1992
- GLP compliance:
- yes
Test material
- Reference substance name:
- 2-[[3-(3-mercapto-1-oxopropoxy)-2,2-bis[(3-mercapto-1-oxopropoxy)methyl]propoxy]methyl]-2-[(3-mercapto-1-oxopropoxy)methyl]propane-1,3-diyl bis[3-mercaptopropionate]
- EC Number:
- 246-893-2
- EC Name:
- 2-[[3-(3-mercapto-1-oxopropoxy)-2,2-bis[(3-mercapto-1-oxopropoxy)methyl]propoxy]methyl]-2-[(3-mercapto-1-oxopropoxy)methyl]propane-1,3-diyl bis[3-mercaptopropionate]
- Cas Number:
- 25359-71-1
- Molecular formula:
- C28H46O13S6
- IUPAC Name:
- 3-[(3-sulfanylpropanoyl)oxy]-2-[(3-[(3-sulfanylpropanoyl)oxy]-2,2-bis{[(3-sulfanylpropanoyl)oxy]methyl}propoxy)methyl]-2-{[(3-sulfanylpropanoyl)oxy]methyl}propyl 3-sulfanylpropanoate (non-preferred name)
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test organisms
- Test organisms (species):
- activated sludge, domestic
- Details on inoculum:
- - Source of inoculum/activated sludge: domestic STP east of Suzhou city (no. 20150731)
- Preparation of inoculum for exposure: sedimented sludge was resuspended in test medium 3 times
- Pretreatment: none
- Concentration of sludge: 4.0 g suspended solid/L
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 28 d
Test conditions
- Details on test conditions:
- TEST CONDITIONS
- Composition of medium: buffer solution with Ca, Mg, and Fe added
- Test temperature: 20+-1 °C
- pH: 7.49
- Aeration of dilution water:
- Suspended solids concentration: 30 mg/L
TEST SYSTEM
- Number of culture flasks/concentration: 2
SAMPLING
- Sampling frequency: weekly
- Sampling method: BOD analyzer
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Toxicity control: yes
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Dose descriptor:
- IC10
- Effect conc.:
- 60 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- inhibition of total respiration
- Details on results:
- All validity criteria were fulfilled:
1) Difference between replicates was 2.9% (<20%)
2) Ref.item was degraded by 83.5% in 14 days ( min.60%)
3) Avg. O2 uptake of inoculum blank was 21.2 mg/L in 28 days (max. 60 mg/L)
4) Toxicity control showed 52.1% degradation on D14 (min. 25%)
Applicant's summary and conclusion
- Conclusions:
- 14 d IC10 = 60 mg/L
- Executive summary:
The toxicity of Di-PETMP to microorganisms was investigated during a ready biodegradation study according to OECD TG 301 F (Manometric Respirometry Test).
The test material, at a concentration of 60 mg C/L, was exposed to activated sewage sludge micro-organisms with culture medium in sealed culture vessels in the dark at approximately 20±1°C for 28 days. Control solutions with inoculum and the standard material, sodium benzoate were used for validation purposes.
The respiration of sodium benzoate by inocculum was determined as toxicity control.
The biodegradation of the item mixture in the toxicity control was found to be 52.1% after 14 days of incubation. Thus, according to the test guidelines, the test item had no inhibitory effect on activated sludge microorganisms at the tested concentration of 2000 mg/L, as the biodegradation in the toxicity control was higher than 25% within 14 days of incubation.
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