Sodium olivoyl glutamate

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

relative density

Type of information:

(Q)SAR

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a (Q)SAR model, with limited documentation / justification, but validity of model and reliability of prediction considered adequate based on a generally acknowledged source

Justification for type of information:

QSAR prediction

1. SOFTWARE
Danish (Q)SAR Database

2. MODEL
http://qsardb.food.dtu.dk/db/index.html

3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
C(=O)(O)C(CCC(=O)O)NC(=O)CCCCCCCC=CCCCCCCCC

4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
http://qsardb.food.dtu.dk/db/index.html

5. APPLICABILITY DOMAIN
http://qsardb.food.dtu.dk/Danish_QSAR_Database_Draft_User_manual.pdf

6. ADEQUACY OF THE RESULT
Prediction fits the purpose of REACH Regulation.

Guideline:

other: REACH guidance on QSARs R6, May 2008

Principles of method if other than guideline:

Density prediction

GLP compliance:

no

Key result

Type:

relative density

Remarks:

QSAR prediction

Density:

ca. 1.06 g/cm³

Remarks on result:

other: QSAR prediction

Remarks:

QSAR prediction

Conclusions:

Predicted density is 1,06 g/cm³.

Executive summary:

Density is 1,06 g/cm³.

Reference 2

Endpoint:

relative density

Type of information:

read-across based on grouping of substances (category approach)

Adequacy of study:

weight of evidence

Justification for type of information:

Important considerations for the read-across were:

Sodium Olivoyl Glutamate (the target chemical) has similar physico-chemical properties as the others members:
- "Aliphatic acid category" (the source chemicals);
- "Amino acid alkyl amides category" (the source chemicals);
- Sodium oleoyl glutamate (the source chemicals);

Key points are that the members share:
- the same structural features
- similar metabolic pathways
- common levels and mode of human health related effects
- function.

Key result

Type:

relative density

Remarks on result:

not measured/tested

Conclusions:

Overall, considering available data on the category members, density is 1,06 g/cm³.

Executive summary:

Density is 1,06 g/cm³.

Key value for chemical safety assessment

Relative density at 20C:

1

Additional information

Overall, considering available data on the category members, density is 1 g/cm³.