Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
(Q)SAR
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification

Data source

Reference
Reference Type:
other: (Q)SAR Report
Title:
Unnamed
Year:
2017
Report Date:
2017

Materials and methods

Test guideline
Qualifier:
no guideline required
Version / remarks:
(Q)SAR
Principles of method if other than guideline:
see attached (Q)SAR report section justification

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: not relevant for (Q)SAR
Details on test material:
not relevant for (Q)SAR

Results and discussion

% Degradationopen allclose all
Key result
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Value:
1.258
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction
Remarks:
Biowin7
Key result
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Value:
0.864
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction
Remarks:
Biowin6 (MITI Non-Linear Biodeg Probability
Key result
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Value:
0.789
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction
Remarks:
Biowin5 (MITI Linear Biodeg Probability)
Key result
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Value:
3.844
Remarks on result:
readily biodegradable based on QSAR/QSPR prediction
Remarks:
Biowin4 (Survey Model - Primary Biodeg

Applicant's summary and conclusion

Interpretation of results:
readily biodegradable
Conclusions:
The readily bidegradation was assessed with different models. All models report hat the substance is ewdily biodegenerable.