Registration Dossier
Registration Dossier
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EC number: 235-030-5 | CAS number: 12058-66-1
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- read accross to Potassium Hexahydroxostannate, based onb the effects of sodium and potasium cation is not relevant
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Vehicle:
- no
- Test organisms (species):
- other: Rainbow trout),
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Hardness:
- see study report
- Test temperature:
- see study report
- pH:
- see study report
- Dissolved oxygen:
- see study report
- Salinity:
- see study report
- Conductivity:
- see study report
- Nominal and measured concentrations:
- see study report
- Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Validity criteria fulfilled:
- yes
- Conclusions:
- LC0 > 100 mg/L
- Executive summary:
The acute toxicity of the test item Potassium Hexahydroxostannate, crystalline M (batch no. 25L138) to fish (Rainbow trout) was determined according to the principles of the OECD- Guideline for Testing of Chemicals No. 203 (1992) from 2013-05-13 to 2013-05-17, at Dr.U.Noack-Laboratorien, Sarstedt, Germany.
A semi-static test with daily renewal of the test media was conducted with the limit concentration of 100 mg/L. Duration of the test was 96 hours. 7 test organisms were exposed for the limit concentration and control, respectively. Water quality parameters temperature, pH-value and 02- saturation measured at 0, 24, 48, 72 and 96 hours were determined to be within the acceptable limits.
The concentrations of Potassium Hexahydroxostannate, crystalline M in the limit concentration and control were analytically verified via ICP-OES by an external test facility (non GLP, see page 4). The concentrations of Potassium Hexahydroxostannate, crystalline M were determined from freshly prepared media after 0 and 72 hours and from the corresponding 24 hours aged media after 24 and 96 h. The measured concentrations in the fresh media were in the range of 101 to 104 % of the nominal values. Recovery rates in the old media of the test media were in the range of 99 % to 102% of the nominal values.
Reference
Description of key information
LC0 > 100 mg/L
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 101 mg/L
Additional information
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