Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 217-683-8 | CAS number: 1929-86-8
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 12.12.2006 - 15.12.2006
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Mecoprop
- EC Number:
- 230-386-8
- EC Name:
- Mecoprop
- Cas Number:
- 7085-19-0
- Molecular formula:
- C10H11ClO3
- IUPAC Name:
- 2-(4-chloro-2-methylphenoxy)propanoic acid
- Test material form:
- liquid
Constituent 1
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Limit test:
- yes
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrationsopen allclose all
- Key result
- Duration:
- 72 h
- Dose descriptor:
- other: ExC50
- Effect conc.:
- > 35.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (dissolved fraction)
- Basis for effect:
- growth rate
- Key result
- Duration:
- 72 h
- Dose descriptor:
- other: EyC50
- Effect conc.:
- > 35.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat. (dissolved fraction)
- Basis for effect:
- other: yield inhibition
Applicant's summary and conclusion
- Executive summary:
The toxicity assessment ofMECOPROP 300 g/L AS POTASSIUM SALTfor algaeDesmodesmus subspicatuswas carried out. Growth inhibition assessment was performed according to the OECD Guideline No 201 (2006), EU method C.3 and Principles of Good Laboratory Practice (GLP, OECD 1997).
The aim of the study was determination of growth inhibition of algaeDesmodesmus subspica-tusafter 24, 48 and 72 h exposure based on average specific growth rate inhibition (expressed as the ErCxin mg/L) and yield inhibition (expressed as the EA in mg/L). The test material was used in one concentration (limit test) — 100 mg/L.
Based on obtained results no growth inhibition effect in tested concentration in relation to control population was observed. According to this, concentration causing 50% inhibition of average specific growth rate ofDesmodesmus subspicatusculture (E,C50/72 h) as well as concentration causing 50% of yield inhibition ofDesmodesmus subspicatusculture (EyC50/72 h) are respectively:
- based on nominal concentration of mecoprop as potassium salt ExC50/72 h value is above 35.6 mg/L, EyC50/72 h value is above 35.6 mg/L,
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
