Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
GLP compliance:
yes
Type of method:
other: visual determination

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline

Results and discussion

Water solubility
Water solubility:
> 1 000 g/L
Conc. based on:
test mat.
Incubation duration:
1 d
Temp.:
20 °C
pH:
12.7
Details on results:
After the stirring period, the test sample was clear and no undissolved test item was observed. It was concluded that the water solubility of R-Quinuclidinol at 20°C was > 1000 g/L. As
water solubility of the substance was determined from visual observation alone to be higher than 1:1 test item:water, no further testing was conducted to determine the actual water solubility value.

Applicant's summary and conclusion

Conclusions:
It was concluded that the water solubility of test substance at 20°C was > 1000 g/L.