Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
Principles of method if other than guideline:
An excess of product is shaked with solvent during 24 hours at 20 deg C. After filtration the concentration in solution is determined with spectrometry.
GLP compliance:
not specified
Medium:
methanol
Solubility:
0.19 g/L
Temp.:
20 °C
Medium:
ethanol
Solubility:
0.14 g/L
Temp.:
20 °C
Medium:
other: 2-propanol
Solubility:
0.12 g/L
Temp.:
20 °C
Medium:
other: dichloromethane
Solubility:
< 0.01 g/L
Temp.:
20 °C
Medium:
other: 2-propanone
Solubility:
0.18 g/L
Temp.:
20 °C
Medium:
ethyl acetate
Solubility:
0.06 g/L
Temp.:
20 °C
Medium:
other: methyl benzene
Solubility:
< 0.01 g/L
Temp.:
20 °C
Medium:
other: 4-methyl-2-pentanone
Solubility:
0.07 g/L
Temp.:
20 °C
Medium:
other: 2-butanone
Solubility:
0.22 g/L
Temp.:
20 °C
Medium:
other: 1-methoxy-2-propanol
Solubility:
0.97 g/L
Temp.:
20 °C

Results of solubility in organic solvents:

 Solvent Solubility in g/L solution 
 N,N-dimethylacetamide 33 
N,N-dimethylformamide 17 
 tetrahydrofurane 0.32 
acetic acid  0.17 
 acetic acid/water (10/90, v/v) (pH = 2.2)  0.04
 acetonitrile  0.06
 2-methoxyethyl ether  0.95
Conclusions:
The solubility of the test substance was determined in different organic solvents and ranged from <0.01 g/L in DCM or methylbenzene to 33 g/L in N,N-dimethylacetamide.

Description of key information

In a supporting study (JPh, 2003) with insufficient documentation, and therefore assigned as Klimisch 4 study, the solubilities of T002487 in different organic solvents were reported.

 Solvent Solubility in g/L solution 
 N,N-dimethylacetamide 33 
N,N-dimethylformamide 17 
 tetrahydrofurane 0.32 
acetic acid  0.17 
 acetic acid/water (10/90, v/v) (pH = 2.2)  0.04
 acetonitrile  0.06
 2-methoxyethyl ether  0.95
 Methanol  0.19
 Ethanol  0.14
 2-Propanol  0.12
 Dichloromethane  <0.01
 2-Propanone  0.18
 Ethylacetate  0.06
 Methylbenzene  <0.01
 4-Methyl-2-pentanone  0.07
 2 -Butanone  0.22
 1 -Methoxy-2-propanol  0.97

Key value for chemical safety assessment

Additional information