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Ecotoxicological information

Long-term toxicity to fish

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Reference
Endpoint:
long-term toxicity to fish, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature
Justification for type of information:
Data is from secondry source
Qualifier:
according to
Guideline:
OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
GLP compliance:
not specified
Analytical monitoring:
yes
Vehicle:
not specified
Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Test type:
other: Static-renewal
Water media type:
freshwater
Total exposure duration:
28 h
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
0.16 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality
Duration:
28 d
Dose descriptor:
LOEC
Effect conc.:
0.5 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
not specified
Conclusions:
The no effect concentration (NOEC) and low effect concentration (LOEC) value of test chemical after 28 days exposure was observed to be 0.16 mg/l and 0.5 mg/l respectively.
Executive summary:

An experiment was conducted to determine the long term toxicity of test chemical by using OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study). In this study test organism used was Oncorhynchus mykiss. The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. By considering the no effect concentration (NOEC) value test chemical is considered to be toxic and can be classified as aquatic chronic 3 for long term toxicity to fish.

Description of key information

An experiment was conducted to determine the long term toxicity of test chemical by using OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study). In this study test organism used was Oncorhynchus mykiss. The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. By considering the no effect concentration (NOEC) value test chemical is considered to be toxic and can be classified as aquatic chronic 3 for long term toxicity to fish.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.16 mg/L

Additional information

An experiment was conducted to determine the long term toxicity of test chemical by using OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study). In this study test organism used was Oncorhynchus mykiss. The no effect concentration (NOEC) and low effect concentration (LOEC) after 28 days was observed to be 0.16 mg/l and 0.5 mg/l respectively. By considering the no effect concentration (NOEC) value test chemical is considered to be toxic and can be classified as aquatic chronic 3 for long term toxicity to fish.