Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 915-656-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 August 2016 to 19 December 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2009
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- 45.275 µm
- Geometric standard deviation:
- 0.003
- Key result
- Percentile:
- D50
- Mean:
- < 60.367 µm
- St. dev.:
- 0.186
- Conclusions:
- Under the conditions of this study the MMAD of the test material was 45.275 µm and the D50 was < 60.367 µm.
- Executive summary:
The particle size of the test material was investigated in accordance with the standardised guideline ISO 13320:2009 and CIPAC MT 187 under GLP conditions.
Following from optical microscope analysis and manual sieve analysis, laser diffraction was performed.
Under the conditions of this study the MMAD of the test material was 45.275 µm and the D50 was < 60.367 µm.
Reference
Optical Microscope Analysis
Standard visual observation: Sample observed to contain fine, medium and coarse, particles of white powder with clusters and agglomerations.
Observation at 100 x magnification: The particles appeared to be irregular shaped crystals. The smallest individual particle size was approximately 3 μm and the largest individual size was approximately 144 μm.
Observation at 400 x magnification: The sample was observed to be made up of both single crystalline particles and agglomerated particles.
Manual Sieve Analysis
Manual sieve analysis indicated that 82.5 % by weight of the sample had a particle size of < 500 μm.
Laser Diffraction Analysis
Using the identified parameters, the particle size was analysed over the range 0.02 μm to 2000 μm.
Results can be seen in Tables 1 and 2.
Table 1: Summary of Test Results
Result |
Average result (µm) of 5 runs |
Volume weighted mean |
93.473 |
Median |
60.367 |
Mode |
58.894 |
Mass median aerodynamic diameter (MMAD) |
45.275 |
d10 - 10 % of material is < |
20.858 |
d50 - 50 % of material is < |
60.367 |
d90 - 90 % of material is < |
202.378 |
2.67 % by volume of sample was see to be < 10.0 µm.
Table 2: Summary of standard deviation results
Result |
Standard deviation of the population (STDVP) |
%STDVP |
d10 - 10 % of material is < |
0.053 |
0.3 |
d50 - 50 % of material is < |
0.186 |
0.3 |
d90 - 90 % of material is < |
3.376 |
1.7 |
d15.78 - 15.78 % of material is < |
0.062 |
0.2 |
Geometric standard deviation (GSD) |
0.003 |
0.1 |
Mass median aerodynamic diameter (MMAD) |
0.14 |
0.3 |
Coefficient of variation for d50 is less than 3 %; d10 and d90 are less than 5 %. Thus repeatability of the characteristic particles in the size distribution are within the acceptable limits as per the ISO 13320-1 test standard.
Description of key information
Under the conditions of this study the MMAD of the test material was 45.275 µm and the D50 was < 60.367 µm.
Additional information
The particle size of the test material was investigated in accordance with the standardised guideline ISO 13320:2009 and CIPAC MT 187 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Following from optical microscope analysis and manual sieve analysis, laser diffraction was performed.
Under the conditions of this study the MMAD of the test material was 45.275 µm and the D50 was < 60.367 µm.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.