Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 271-685-3 | CAS number: 68604-33-1 This substance is identified by SDA Substance Name: C14-C18 and C16-C18 unsaturated alkyl carboxylic acid ammonium salt and SDA Reporting Number: 04-006-01.
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- Read-across (analogue): For justification of read-across see section 13.2.
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across: supporting information
- Reason / purpose for cross-reference:
- read-across: supporting information
- Reason / purpose for cross-reference:
- read-across: supporting information
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- >= 21 - <= 217 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Conclusions:
- Based on read across studies for short term toxicity to fish on chemically similar substances the LC50(fish, 96h) for the target substance Fatty acids, C14-18 and C16-18-unsatd., ammonium salts is estimated to be >=21 mg/l (to <= 217mg/l).
Reference
Description of key information
Based on read across studies for short term toxicity to fish on chemically similar substances the LC50(fish, 96h) for the target substance Fatty acids, C14 -18 and C16 -18 -unsatd., ammonium salts is estimated to be >=21 mg/l (to <= 217mg/l).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 21 mg/L
Additional information
Several publication are available in which the acute toxicity to fish of the analogue substances (Sodium oleate, Sodium myristate, Sodium palmitate, Sodium stearate) were determined. Therefore,
after acclimatization red killifish (Oryzias latipes) were exposed to several concentrations of the read across substance. The test followed a semi-static procedure with an exposure time of 96 h. As results, the following LC50 values in freshwater were determined: 217 mg/L for sodium oleate, 118 mg/L for sodium myristate, 150 mg/L for sodium palmitate and 125mg/L for sodium stearate.
Additionally, an acute aquatic toxicity test was conducted on fish to assess the LC50 (96 h) of sodium myristate. The study was conducted in 2000 according to OECD guideline 203 and in compliance with GLP by the MOE (Ministry of the Environment in Japan). As a result, an LC50 of >21 mg/L was revealed.
Based on the structural similarity of the target substance to the analogue substances the results of the acute toxicity to fish of the source substances can be assigned to the target substance.
The supporting information of the short term toxicity to fish of the analogue substances: sodium oleate (LC50(fish, 96h): >100mg/l), sodium stearate (LC50(fish, 96h): >100mg/l) and sodium laurate (LC50(Oryzias latipes, 96h): 11mg/l) are stated below. But these information are less appropriate for the read-across projection to short term toxicity to fish of the target substance (laurate is only an impurity).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
