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EC number: 259-952-2 | CAS number: 56038-13-2
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1985
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- - Principle of test:
The solubility of the test item in water was measured in units of weight of test item per weight of saturated solution (w/w %, g/100 g) and in units of weight of test item per volume of saturated solution (w/v %, g/100 ml) .
- Short description of test conditions: 20 °C - GLP compliance:
- not specified
- Type of method:
- flask method
- Specific details on test material used for the study:
- The measurements were made on production grade (PG), purified (P) and test item containing niacinamide (N) . The values used for this dossier are based on production grade (PG).
- Key result
- Water solubility:
- ca. 283 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Incubation duration:
- ca. 22 h
- Temp.:
- 20 °C
- Remarks on result:
- other: pH was not measured
- Details on results:
- The solubility of sucralose in water has been measured. The solubility in water of production grade was found to be: 283 g/L at 20 °C
- Conclusions:
- The solubility of sucralose in water has been measured. The solubility in water of production grade was found to be: 283 g/L at 20 °C
Reference
| test item (PG) | |||
| 1st | 2nd | ||
| HPLC assay test item soln. Diluted to 100 ml | g/100 ml | 1.14 | 1.12 |
| Weight of original solution | g | 4.3824 | 4.4249 |
| Test item in original solution w/w % | g/100 g | 26.0 | 25.3 |
| Average test item in original solution w/w % | g/100 g | 25.7 | |
| test item in original solution w/v % | g/100 ml | 28.5 | 28.0 |
| Average test item in original solution w/v % | g/100 ml | 28.3 | |
Description of key information
The solubility of sucralose in water has been measured in a well documented study meeting scientific principles. The solubility in water of production grade was found to be: 283 g/L at 20 °C
Key value for chemical safety assessment
- Water solubility:
- 283 g/L
- at the temperature of:
- 20 °C
Additional information
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