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Diss Factsheets
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EC number: 251-833-3 | CAS number: 34122-40-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- yes
- Type of method:
- flask method
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Batch: 670500
- Purity: 99.9% - Key result
- Water solubility:
- > 3.172 - < 4.247 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 7
- Remarks on result:
- other: pH and temperature of the initial solubility were not reported.
- Conclusions:
- While TAOBN does demonstrate some solubility in water, it is not technically possible to measure water solubility using OECD TG105. Based on the initial solubility study, the solubility of TAOBN is >3.172 and <4.247 g/L.
Reference
The Flask Method Results, and subsequent solubility investigations identified that TAOBN, when put into solution, forms a constitutional isomer, or tautomer, which interconverts in solution. Thus the following results are reported:
- Tautomer generation is dependant on both time and the concentration of TAOBN in solution. This conclusion is based on two independent calibration studies and the available data from the measurement of saturated and nearly saturated samples on the UV-Vis.
- Initial solubility of TAOBN in water is approximately 3-5 g/L. This was measured by using incremental additions of TAOBN to 100 ml of water and visibly observing solution clarity.
- A concentration of 0.5 g/L of TAOBN generated negligible amount of tautomer (measured by UV-Vis) after 72 hours in solution based on minimal shift in UV-Vis lambda max.
- A concentration of 11 g/L (assumed saturated for the Flask Method Study) generated significant tautomer after 72 hours in solution based on the major shift in lambda max.
- Our TAOBN manufacturing experience demonstrates that upon removal from solution (through isolation and drying), the co-tautomer system reverts to the standard TAOBN molecule.
Description of key information
While TAOBN does demonstrate some solubility in water, it is not technically possible to measure water solubility using OECD TG105. Based on the initial solubility study, the solubility of TAOBN is >3.172 and <4.247 g/L.
Key value for chemical safety assessment
- Water solubility:
- 3.172 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.