Registration Dossier
Registration Dossier
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EC number: 945-952-6 | CAS number: -
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
- GLP compliance:
- yes (incl. QA statement)
- Test type:
- acute toxic class method
- Limit test:
- no
Test material
- Reference substance name:
- 3-Mercaptopropyl-functionalized silica gel
- EC Number:
- 945-952-6
- Molecular formula:
- Si-CH2-CH2-CH2-SH
- IUPAC Name:
- 3-Mercaptopropyl-functionalized silica gel
Constituent 1
Test animals
- Species:
- rat
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- corn oil
- Doses:
- 300 and 2000 mg/kg body weight
- No. of animals per sex per dose:
- 6
Results and discussion
Effect levels
- Key result
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
- Mortality:
- none
- Clinical signs:
- other: no systemic signs of toxicity
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
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