Registration Dossier
Registration Dossier
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EC number: 208-021-9 | CAS number: 505-84-0
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 2011-01-24 to 2011-01-31
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- Adopted 27 July 1995
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Water solubility:
- 3.65 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- >= 4.39 - <= 5.61
- Details on results:
- Average water solubility is 3.647 g/L. Standard deviation is 0.141 g/L. Relative standard deviation is 3.85 %.
The following quality criterion was fulfilled. The concentration from at least the last two vessels agree with the required reproducibility, i.e., < 15 %. - Conclusions:
- The water solubility of the test substance propylal is 3.65 g/L at the temperature of 20°C (with standard uncertainty of 0.14 g/L).
- Executive summary:
Water solubility test was performed for the test substance, propylal. Flask method was used.
Test was performed according to the Method A.6., Water Solubility, Council Regulation (EC) No.440/2008, Published in O.J. L 142, 2008.
The concentration of the substance in aqueous solution was determined by GC method (validated GC method: Study No. 40/10/48 - Propylal, validation of GC method, VUOS-CETA Report No.10-379, 2010).
Testing was performed at the temperature of 20°C.
The water solubility of the test substance propylal is 3.65 g/L at the temperature of 20°C (with standard uncertainty of 0.14 g/L).
Reference
The results of the determination of the test substance solubility are presented in the table below:
Day |
pH of saturated solution |
Solubility of first injection (g/L) |
Solubility of second injection (g/L) |
Mean Solubility (g/L) |
1 |
5.61 |
3.503 |
3.495 |
3.499 |
2 |
4.91 |
3.700 |
3.626 |
3.663 |
3 |
4.39 |
3.672 |
3.885 |
3.779 |
Average |
3.647 |
|||
Standard deviation |
0.141 |
|||
Relative standard deviation |
3.85 |
|||
Description of key information
Key value for chemical safety assessment
- Water solubility:
- 3.65 g/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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