5-bromo-5-nitro-1,3-dioxane

Guidance on Safe Use

First-aid measures

· After inhalation: Remove from source of exposure. If irritation or signs of toxicity occur, seek medical attention.

· After skin contact: Take off any clothing that the product touched. Rinse skin with running water for 15 to 20 minutes. Seek medical attention if irritation or signs of toxicity occur.

· After eye contact: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists, get medical advice/attention. Wash hands after handling.

· After swallowing: Rinse mouth with water. If irritation or signs of toxicity occur, seek medical attention.

Fire-fighting measures

Suitable extinguishing agents:

Dry chemical, carbon dioxide (CO2), water spray or regular foam.

- Caution: CO2 will displace air in confined spaces and may cause an oxygen-deficient atmosphere.

- For larger fires: There are no unique chemical or reactivity hazards that would impact firefighting decisions related to this product. Use firefighting measures that suit the environment.

There are no unique chemical or reactivity hazards that would impact firefighting decisions due to the chemicals in this product.

For large fires, wear appropriate heat- and flame-resistant personal protective equipment and an approved positive-pressure, self-contained breathing apparatus.

Accidental release measures

Minimize exposure by using appropriate personal protective equipment. Stop leak if possible. Keep unprotected persons away.

Prevent liquid and vapor from entering sewage system, storm drains, surface waters, and soil.

Blot up small volumes of spilled or spattered product with paper towels or similar materials. - Contain larger spills by placing absorbants around the outside edges of the spill. Absorb with any material suitable for water-based liquids - e.g. paper towels, universal sorbents, sand, diatomite, sawdust, etc.

Clean the affected area. Suitable cleaners are: - warm water and detergent or similar cleansing agent

NOTE FOR LARGE-VOLUME SPILL:

Select a disinfectant that does not bubble, effervesce or otherwise generate aerosols.

- Do not use excess disinfectant.

- Do not use a disinfectant if you do not have the proper facility, equipment and other appropriate protective measures available to work with it safely.

Handling and storage

Avoid direct contact with material. If handled, wash thoroughly. Practice general safety precautions.

Information about protection against explosions and fires: No special measures required.

Requirements to be met by storerooms and containers:

Store only in the original container.

Refer to the package insert or product label for additional information on storage conditions for product quality.

Information about storage in one common storage facility: Store in original packaging.

Further information about storage conditions: Protect from heat and direct sunlight.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

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Shipping

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SpecialProvisions

Exposure controls / personal protection

General protective and hygienic measures: Always maintain good housekeeping and follow general precautionary measures. Do not eat, drink or store food and beverages in areas where chemicals or specimens are used. Wash hands before breaks, after handling reagents and specimens, and at the end of the workshift.

Breathing equipment: Normal use and storage of product - respiratory protection is not necessary if room is well ventilated.

Small-volume spills (e.g. small enough to clean up with a paper towel or small sorbent pad) - respiratory protection should not be necessary if room is well ventilated.

Other unusual conditions (e.g. volume spilled too big to clean up with materials in arm's reach) - Use appropriate air-purifying respirator if airborne chemical concentrations may exceed the exposure limit (if any) listed above.

Hazardous Materials Emergencies or Firefighting - use approved respiratory protection.

Take precautions if chemical concentrations exceed the exposure limits, if any.

Protection of hands: Wear impervious gloves if hand contact with the material is anticipated. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Material of gloves and breakthrough time of the glove material: The glove material must be suitable for use in a microbiological laboratory and have a measured breakthrough time of at least 30 minutes, such as those with a Class 2 protection index per EN374 (or equivalent standard applicable in your region). NOTE: This recommendation applies only to the product stated in this Safety Data Sheet. When dissolving in or mixing with other substances, contact the supplier of approved gloves.

Eye protection: Wear safety glasses or other protective eyewear. If splash potential exists, wear full face shield or goggles.

Body protection: Normal use: protect personal clothing from spatters and small spills. Wear a laboratory coat (or other

protective clothing required by your institution). Larger spills (e.g. that can saturate cloth): wear appropriate

water-repellant covering over clothing.

Stability and reactivity

Reactivity No further relevant information available.

Thermal decomposition / conditions to be avoided: No decomposition if used and stored according to specifications.

Disposal considerations

Dispose in accordance with national, state and local regulations and institutional requirements. Waste containing this product may be considered hazardous per state or local regulations. The following may be particularly important when identifying appropriate disposal:

Uncleaned packagings For disposal of contaminated packaging, refer to applicable local regulations and institutional policies.

Recommendation for disposal of packaging: Non-contaminated packaging may be used for recycling. Refer to applicable local regulations and institutional policies. For disposal of contaminated packaging, refer to applicable local regulations and institutional policies.

Recommended cleaning agent: Water with cleansing agents, if necessary.