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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
Version / remarks:
Flask method
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
336.43 g/L
Conc. based on:
test mat. (dissolved fraction)
Loading of aqueous phase:
5 000 g/L
Incubation duration:
> 1 - < 3 d
20 °C
> 5.82 - < 5.93
The water solubility of test item “Direct Yellow 147” was performed according to OECD 105 (1995) and EPA Test Guideline OCSPP 830.7840 by an HPLC-UV method. The analytical method used for the analyte quantification proved to be specific and linear. The water solubility of 2.5 g of “Direct Yellow 147” at 20°C in 5.0 mL of water with flask method proved to be 336.43 g/L. An additional test was performed using the worst case scenario, as described in guidelines. The result
corresponds to about 98% of recovery with respect to the theoretical initial amount of sample in solution, so as verified for the working solutions of the final test. Therefore the result of water solubility is strictly related to the amount of substance used to perform the test and the content of water added.
Executive summary:

336.43 g/L

Description of key information

In an OECD 105 study performed on the registered substance, the water solubility measured by HLPC was 336.43 g/L.

Key value for chemical safety assessment

Water solubility:
336.43 g/L
at the temperature of:
20 °C

Additional information