Oligo

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04 - 07 Dec 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Remarks:

Flask method: only 1 day agitation period, see "Any other information on materials and methods incl. tables" for explanation.

Reason / purpose for cross-reference:

reference to other study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

27 July, 1995

Deviations:

yes

Remarks:

The test was interrupted after 1 day because the substance was under the limit of quantification of the analytical method.

GLP compliance:

yes

Type of method:

flask method

Water solubility:

< 0.509 mg/L

Temp.:

20 °C

pH:

>= 6.1 - <= 6.2

Test results

	pH	Measured concentration of test item in test solution (mg/L)	Average
Sample-a	6.2	< 0.509
Sample-b	6.1	< 0.509	< 0.509

 

Water solubility of test item: < 0.509 mg/L (20 °C)

 

Discussion

The test item was hardly soluble in water and the water solubility was less than the concentration calculated from the determination limit. The analytical method was judged to be valid because an acceptable recovery rate (average of recovery rates: 98.7%) was obtained in the recovery test. Therefore, it was concluded that the test results were acceptable.

Description of key information

Solubility in water: < 0.509 mg/L at 20 °C (OECD Guideline 105, flask method)

Additional information

The test item was hardly soluble in water and the water solubility was less than the concentration calculated from the determination limit.