2-amino-6-methyl-4-propyl-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-one

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Principles of method if other than guideline:

See 'Any other information on materials and methods incl. tables'.

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

RESULTS

- Screening test: The test substance melted and ignited on application of the ignition source, but self-extinguished on its removal. It did not propagate combustion and the burning time over 200 mm could not be determined.

- Full test series: Not required.

CONCLUSIONS

(i) The test substance did not propagate combustion.

(ii) In accordance with the criteria of UN Test N1, the test substance is not classified as a flammable solid.

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance did not propagate combustion.

Executive summary:

To determine the the ability of the substance to propagate combustion a study was performed according to UN Test N.1: “Test Method for Readily Combustible Solids”. In this study the test substance melted and ignited on application of the ignition source, but self-extinguished on its removal. It did not propagate combustion and the burning time over 200mm could not be determined. In accordance with the criteria of UN Test N.1, the test substance is not classified as a flammable solid.

Reference 2

Endpoint:

pyrophoric solids

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.2 (Test method for pyrophoric solids)

Principles of method if other than guideline:

See 'Any other information on materials and methods incl. tables'.

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

ignition time on contact with air

Remarks on result:

no ignition within 5 minutes

RESULTS

There were no signs of ignition during dropping or throughout the 5 minute observation period.

CONCLUSIONS

- The test substance does not spontaneously ignite on contact with air at ambient temperatures.

- In accordance with the criteria of UN Test N.2, the test substance is not classified as pyrophoric solid.

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance does not spontaneously ignite on contact with air at ambient temperatures.

Executive summary:

To determine the ability of the substance to spontaneously ignite on contact with air at ambient temperatures a study was performed according to UN Test N.2: “Test Method for Pyrophoric Solids”. In this study there were no signs of ignition during dropping or throughout the 5 minute observation period. In accordance with the criteria of UN Test N.2, the test substance is not classified as pyrophoric solid.

Reference 3

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)

Principles of method if other than guideline:

See 'Any other information on materials and methods incl. tables'.

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

100 mm sample cube at 140°C

Result:

negative outcome (no effect observed)

RESULTS

- 100 mm container at 140 °C: The test substance shows no exothermic activity, with the temperature at the centre of the sample settling out at the same level as the oven air temperature. As this constitutes a negative result, no further testing was necessary.

CONCLUSIONS

- The test substance shows no signs of self-heating when tested in a 100 mm cubic wire mesh container at 140 °C.

- In accordance with the criteria of UN Test N.4, the test substance is not classified as a self-heating substance.

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance shows no signs of self-heating when tested in a 100 mm cubic wire mesh container at 140°C.

Executive summary:

To determine the ability of the substance to self-heat a study was performed according to UN Test N.4: “Test Method for Self-Heating Substances”. In this study there were no signs of self-heating when tested in a 100 mm cubic wire mesh container at 140 °C. In accordance with the criteria of UN Test N.4, the test substance is not classified as a self-heating substance.

Reference 4

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.5 (Test method for substances which in contact with water emit flammable gases)

Principles of method if other than guideline:

See 'Any other information on materials and methods incl. tables'.

GLP compliance:

yes (incl. QA statement)

Key result

Test procedure:

step 1

step 2

step 3

step 4

Identity of evolved gas:

not applicable as no gas evolved

Remarks on result:

no reaction with water observed

RESULTS

- Step 1: No gas evolved.

- Step 2: No gas evolved.

- Step 3: No gas evolved.

- Step 4: Sample preparation: ground and sieved to <500 µm; Room temperature: 20 - 21°C; Water temperature: 21°C.

No significant quantities of gas were evolved on contact with water over a period of 7 hours in each of the three tests.

CONCLUSIONS

- The test substance does not evolve flammable gases on contact with water.

- In accordance with the criteria of UN Test N.5, the test substance is not classified as a substance which, in contact with water, emits flammable gases.

Interpretation of results:

GHS criteria not met

Conclusions:

The test substance does not evolve flammable gases on contact with water.

Executive summary:

To determine the ability of the substance to react with water a study was performed according to UN Test N.5: “Test Method for Substances Which in Contact with Water Emit Flammable Gases”. In this study no significant quantities of gas were evolved on contact with water over a period of 7 hours in each of the three tests. In accordance with the criteria of UN Test N.5, the test substance is not classified as a substance which, in contact with water, emits flammable gases.

Reference 5

Endpoint:

flammability, other

Remarks:

Self-reactive substances

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: UN Test H.4: “Heat Accumulation Storage Test”.

Principles of method if other than guideline:

See 'Any other information on materials and methods incl. tables'.

GLP compliance:

yes (incl. QA statement)

RESULTS

At no point during the test did the sample temperature exceed the test temperature by 6 °C or more, indicating that the SADT is greater than 75 °C.

CONCLUSIONS

- The Self-Accelerating Decomposition Temperature is greater than 75 °C.

- In accordance with the criteria of UN Test H.4, the test substance is not classified as a self-reactive substance.

Interpretation of results:

GHS criteria not met

Conclusions:

The Self-Accelerating Decomposition Temperature (SADT) is greater than 75 °C.

Executive summary:

To determine the Self-Accelerating Decomposition Temperature (SADT) of the test substance a study was performed according to UN Test H.4: “Heat Accumulation Storage Test”. At no point during the test did the sample temperature exceed the test temperature by 6 °C or more, indicating that the SADT is greater than 75 °C.

Description of key information

- Flammable solids: No combustion and the burning time over 200 mm, UN Test N.1, GLP, preliminary screening test, Jackson 2015

- Pyrophoric properties: No spontaneous ignition, UN Test N.2, GLP, Jackson 2015

- Self-heating properties: No self-ignition observed, UN Test N.4, GLP, 100 mm sample cube at 140 °C, Jackson 2015

- Water reactivity: No gas evolved, UN Test N.5, GLP, preliminary screening tests, Jackson 2015

- Self-reactive properties: SADT is greater than 75 °C, UN Test H.4, GLP, Jackson 2015

Key value for chemical safety assessment

Flammability:

not classified

Additional information

- Flammable solids: In this study the test substance melted and ignited on application of the ignition source, but self-extinguished on its removal. It did not propagate combustion and the burning time over 200 mm could not be determined.

- Pyrophoric properties: In this study there were no signs of ignition during dropping or throughout the 5 minute observation period.

- Self-heating properties: In this study there were no signs of self-heating when tested in a 100 mm cubic wire mesh container at 140 °C

- Water reactivity: In this study no significant quantities of gas were evolved on contact with water over a period of 7 hours in each of the three tests.

- Self-reactive properties: At no point during the test did the sample temperature exceed the test temperature by 6 °C or more, indicating that the SADT is greater than 75 °C.