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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From April 04, 2017 to April 05, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
other: OECD Guideline 105
Deviations:
no
GLP compliance:
not specified
Type of method:
flask method
Partition coefficient type:
octanol-water
Key result
Type:
log Pow
Partition coefficient:
> 2.59
Temp.:
20 °C
pH:
7
Conclusions:
Under the study conditions, the solubility of the test substance in n-octanol was determined at >1.5 kg/L or rather unlimited (at 20 °C). The test substance partition coefficient is >2.59 or rather unlimited (at 20°C).
Executive summary:

A study was conducted to determine the partition coefficient of the test substance according to OECD Guideline 105. The tests were performed at 20°C. With 3 g of test substance being mixed into 1.64 g of n-octanol, a clear liquid with a total weight of 4.64 g has been formed. This is equivalent to 64.7% (w/w) of test substance in solution or a concentration of 1.5 kg/L. Under the study conditions, the solubility of the test substance in n-octanol was determined at >1.5 kg/L or rather unlimited (at 20°C). The test substance partition coefficient is >2.59 or rather unlimited (at 20°C) (Schwarzkopf, 2017).

Description of key information

The partition coefficient was determined according to EU Method A.6 (Schwarzkopf, 2017).

Key value for chemical safety assessment

Log Kow (Log Pow):
2.59
at the temperature of:
20 °C

Additional information

>2.59