Registration Dossier

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

in vitro Bacterial Reverse Gene Mutation Assay- Negative (conducted on substance); OECD 471; Reliability 1

in vitro gene mutation study in mammalian cells: Comet Assay: Negative (Read across from BPAF); EPA OPPTS 870.5300; Fic et al., 2013

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Justification for classification or non-classification

Based on in vitro gene mutation study in bacteria, conducted on the analogous target substance, and supported by in vitro gene mutation study in mammalian cells - conducted on the source analogous substance, the target substance does not meet the classification criteria for mutagenicity in accordance with Regulation (EC) No 1272/2008 (CLP).