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Physical & Chemical properties

Water solubility

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Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Principles of method if other than guideline:
Currenta internal SOP 00190 Version 3, this SOP corresponds to the Council Regulations EC No 440/2008, Guideline Part A – Methods for the Determination of the Physical-Chemical Properties, A.6, “Water solubility” (adopted, May 2008) and to the OECD Guidelines for testing of chemicals No: 105 “Water solubility“ (adopted 27thJuly 1995).
GLP compliance:
yes
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
flask method
Key result
Water solubility:
ca. 100 other: Gramm
Conc. based on:
test mat.
Incubation duration:
ca. 5 - <= 15 min
Temp.:
20 °C
Remarks on result:
completely miscible
Details on results:
Procedure:
Solubility tests in ratios of 1+10, 1+1 and 10+1 of the test item Carbazat (KGD1409) in demineralized water were prepared in 20 ml beaded rim bottles. The exact initial weights of the test item and the exact weights of the demineralized water are listed in table 1. The bottles were tightly stoppered and then agitated with a magnetic stirrer and alternate mechanical shaking at room temperature (20 °C).
The results of the tests shows, that the test item Carbazat (KGD1409) was soluble in demineralized water in each ratio after 5 – 15 minutes.
Table 1: Initial weights and volumes of the test item Carbazat (KGD1409)
Test at 20 °C
Bottle 1 Ratio 1+10
Bottle 2 Ratio 1+1
Bottle 3 Ratio 10+1
Initial weight of the test item [g]
1.01
5.16
9.96
Volume of demineralized water in [g]
10.08
5.15
0.99
Appearance
Clear solution
Clear solution
Clear solution
9.1.2. Result
The results of the tests shows, that the test item Carbazat (KGD1409) was soluble in demineralized water in each ratio. Therefore no more tests for the water solubility of the test item were necessary.

Description of key information

The results of the tests shows, that the test item Carbazat (KGD1409) was soluble in demineralized water in each ratio.

Key value for chemical safety assessment

Water solubility:
100
at the temperature of:
20 °C

Additional information