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Environmental fate & pathways

Hydrolysis

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Description of key information

A GLP-compliant hydrolysis study was performed according to OECD 111. In the preliminary Tier 1 study, a decrease in concentration of >10% (i.e. 98%) was observed after 5 days at 50°C at pH 4, 7 and 9, likely due to volatility. Therefore a Tier 2 study was performed. using minimum headspace in the test vessels. The test substance was stable in this test: < 10% hydrolysis after 5 days at 50°C was observed at pH 4, 7 and 9 in the Tier 2 test. This corresponds with a half-life time at 25°C of > 1 year and the substance can be considered hydrolytically stable at pH 4, 7 and 9.

Key value for chemical safety assessment

Half-life for hydrolysis:
1 yr
at the temperature of:
25 °C

Additional information