Registration Dossier

Ecotoxicological information

Toxicity to aquatic plants other than algae

Administrative data

Endpoint:
toxicity to aquatic plants other than algae
Type of information:
(Q)SAR
Adequacy of study:
other information
Study period:
2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
Disregarded study due to the availability of a new axperimental study

Data source

Reference
Reference Type:
other: QSAR Prediction
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Guideline:
other: REACH Guidance on QSAR R.6

Test material

Constituent 1
Chemical structure
Reference substance name:
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid
EC Number:
228-475-1
EC Name:
(3β,20β)-3-acetoxy-11-oxoolean-12-en-29-oic acid
Cas Number:
6277-14-1
Molecular formula:
C32H48O5
IUPAC Name:
(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-acetyloxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
Test material form:
solid
Specific details on test material used for the study:
Danish (Q)SAR database. EPI ECOSAR. Classes Esters-acid; Vinyl/Allyl Ketones-acid

Results and discussion

Effect concentrationsopen allclose all
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
7.01 mg/L
Conc. based on:
other: Esters.
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
11.55 mg/L
Conc. based on:
other: Vinyl/Allyl/Propargyl Ketones

Applicant's summary and conclusion

Validity criteria fulfilled:
yes