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Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
For justification of read across see category justification attached to category object.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
3,6,9,12-tetraoxahexadecan-1-ol
EC Number:
216-322-1
EC Name:
3,6,9,12-tetraoxahexadecan-1-ol
Cas Number:
1559-34-8
Molecular formula:
C12H26O5
IUPAC Name:
3,6,9,12-tetraoxahexadecan-1-ol
Test material form:
liquid

Results and discussion

Remarks on result:
other: not mutagenic based on read across and QSAR prediction

Applicant's summary and conclusion

Executive summary:

Based on data from category members and supported by reliable QSARs, this substance is expected to produce negative results from standard genotoxicity/mutagenicity assays.

interpolating from category members, cytotoxicity is not expected up to the limit dose.