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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Toxicity to green algae:

reaction mass of 3,6,9,12-tetraoxahexadecan-1-ol and 2-(2-(2-butoxyethoxy)ethoxy)ethanol: EC50 (72hr) = 2490mg/L

2-(2-(2-butoxyethoxy)ethoxy)ethanol: EC50 (72hr) = 804mg/L

2-(2-butoxyethoxy)ethanol: EC50(72hr) = 1101mg/L

QSAR prediction for tetrathylene glycol butyl ether: EC50 (96hr) = 3200mg/L

Key value for chemical safety assessment

EC50 for freshwater algae:
2 490 mg/L

Additional information

The QSAR predicts that the toxicity to algae decreases with the increasing molecular weight within the series of ethylene glycol butyl ethers. The toxicity of tetraethylene glycol butyl ether is predicted to be significantly less than that of triethylene glycol which provides support to the use of data from the latter, or mixtures of the tri and tetra, as conservative alternative to data on the pure tetra. The key value is chosen from a reliable guideline study that used a mixture of tri and tetraethylene glycol butyl ether.