Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

For Oenanthic Ether the following results were derived:

Species

Guideline / Method

Result

Remarks

Daphnia magna

ECOSAR esters

48-h EC50: 1.456 mg/L

Key study, Rel. 2. Value derived from QSAR calculation using measured log Kow of 4.6. Other characteristics are from Ethyl dodecanoate/laurate (CAS# 106 -33 -2), being the key constituent of the ether.

Green algae

ECOSAR esters

72-h ErC50: 0.411 mg/L

72-h ErC10: 0.245 mg/L

Key study, Rel. 2.  

Value derived from QSAR calculation using measured log Kow of 4.6. Other characteristics are from Ethyl dodecanoate/laurate (CAS# 106 -33 -2), being the key constituent of the ether.

Additional information

The composition of Oenanthic ether is presented below

Overview table of the Oenanthic constituents and impurities > 10 and 1%, respectively

Chemical names for

 

Oenanthic ether#

ethyl octanoate (C8*)

ethyl decanoate (C10*)

ethyl dodecanoate (C12*)

ethyl tetra-decanoate (C14*)

ethyl hexa-decanoate (C16*)

ethyl octa-decanoate (C18*)

ethyl (9Z)-octadec-9-enoate (C18*)

ethyl (9Z,12Z)‐octadeca‐,12‐di enoate (C18*)

Target

 

 

 

 

 

 

 

 

CAS#

106-32-1

110-38-3

106-33-2

124-06-1

628-97-7

111-61-5

544-35-4

111-62-6

Structure

% in product

<10

<10

35-55

15-30

5-15

<10

<10

<10

EC No.

945-734-0#

 

 

 

 

 

 

 

 

Vp (Pa)

0.12 meas)#

 31.4

(est.)

 5.70

(est.)

 1.17

(est.)

 0.34

(est.)

0.036

(est.)

 0.0084

(est.)

 0.0081

(est.)

 0.0067

(est.)

WS (mg/L)

1.6 (meas)#

 45.6

(est.)

 4.8

(est.)

 0.41

(est.)

 0.037

(est.)

 0.0037

(est.)

 0.0004

(est.)

 0.0006

(est.)

 0.0009

(est.)

Log Kow

4.6 (meas)#

 3.8

(est.)

 4.8

(est.)

 5.8

(est.)

 6.8

(est.)

 7.7

(est.)

 8.4

(est.)

 8.5

(est.)

 8.3

(est.)

 

For assessing the aquatic toxicity the log Kow of 4.6 is used, which is the only peak in the chromatogram and is related to ethyl dodecanoate, because this constituent has the highest concentration in the product. With this log Kow the lowest acute aquatic toxicity value is between 0.1-1 mg/l and also the chronic algae is within this range. Though higher log Kow are estimated and are expected for the longer chains, this log Kow of 4.6 is considered sufficiently conservative also for the two minor constituents. The impurities with the higher chain lengths are expected to have toxicities > water solubility.