Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 03 January 2018 to 31 January 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
1995
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Version / remarks:
1998
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid
Details on test material:
- Appearance: Light tan solid
- Storage conditions: At room temperature protected from light

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
194.5 °C
Decomposition:
yes
Decomp. temp.:
195 °C
Remarks on result:
other: Decomposition started during melting.

Any other information on results incl. tables

DSC EXPERIMENT 1

Endothermic peak between 175°C and 200°C (extrapolated onset temperature: 194.505°C) directly followed by an exothermic effect starting at 200°C. The endothermic effect was most likely obtained due to melting of the test item. The exothermic effect was probably obtained due to reaction and/or decomposition of the test item. After the experiment, a dark brown molten residue remained in the sample container (original colour: light tan). 

DSC EXPERIMENT 2

In order to investigate the melting peak, Experiment 2 was stopped directly after the endothermic peak.  Extrapolated onset temperature: 194.545°C. After the experiment, a light yellow molten residue remained in the sample container. The change of the colour indicated reaction and/or decomposition of the test item. 

 

DATA HANDLING

The melting temperature was determined as the mean extrapolated onset temperature of Experiment 1 and Experiment 2.

Applicant's summary and conclusion

Conclusions:
The melting temperature of the substance was determined to be 194.5°C.
Executive summary:

Differential Scanning Calorimetry (DSC) experiments were performed in a GLP study according to EC A.1, OECD 102 and OPPTS 830.7200.

The melting temperature of the substance was determined in duplicate obtaining a mean value of 194.5°C. Reaction and/or decomposition of the substance started during melting.