Registration Dossier
Registration Dossier
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EC number: 285-397-0 | CAS number: 85085-75-2 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Thymus zygis, Labiatae.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1979
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Monograph used by the fragrance industry.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Monographs on Fragrance Raw Materials
- Author:
- D. L. J. Opdyke
- Year:
- 1 979
- Bibliographic source:
- p.704
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- RIFM protocol in 1973
- GLP compliance:
- no
Test material
- Reference substance name:
- Thyme, Thymus zygis, ext.
- EC Number:
- 285-397-0
- EC Name:
- Thyme, Thymus zygis, ext.
- Cas Number:
- 85085-75-2
- Molecular formula:
- not relevant for a UVCB substance
- IUPAC Name:
- Thyme, Thymus zygis, ext.
- Test material form:
- liquid: volatile
- Details on test material:
- UVCB
1
Test animals
- Species:
- rat
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- approximate LD50
- Effect level:
- > 3 750 - < 5 670 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Conclusions:
- The acute oral LD50 value in rats was reported 4.70 g/kg (Moreno, 1973).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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