Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 285-397-0 | CAS number: 85085-75-2 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Thymus zygis, Labiatae.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1979
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Monograph used by the fragrance industry.
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Monographs on Fragrance Raw Materials
- Author:
- D. L. J. Opdyke
- Year:
- 1 979
- Bibliographic source:
- p.704
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- RIFM protocol in 1973
- GLP compliance:
- no
Test material
- Reference substance name:
- Thyme, Thymus zygis, ext.
- EC Number:
- 285-397-0
- EC Name:
- Thyme, Thymus zygis, ext.
- Cas Number:
- 85085-75-2
- Molecular formula:
- not relevant for a UVCB substance
- IUPAC Name:
- Thyme, Thymus zygis, ext.
- Test material form:
- liquid: volatile
- Details on test material:
- UVCB
1
Test animals
- Species:
- rat
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- approximate LD50
- Effect level:
- > 3 750 - < 5 670 mg/kg bw
- Based on:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- Category 5 based on GHS criteria
- Conclusions:
- The acute oral LD50 value in rats was reported 4.70 g/kg (Moreno, 1973).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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