Registration Dossier
Registration Dossier
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EC number: 945-003-6 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key study- In Vitro Skin Corrosion and Irritation Tests Using the Epiderm™ Skin Model - Read across from CAS: 422-91-3 - Negative for corrosion and positive for skin irritation.
Key study - Bovine Corneal Opacity and Permeability Assay - Read across from CAS: 422-91-3 - Inconclusive.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Based on read across data from the analogue CAS 422-91-3, the in vitro skin corrosion and irritation assays, the test substance was predicted to be non-corrosive, but irritating to the skin. Therefore, the test substance is classified as Cat 2 (H315: causes skin irritation) according to EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.
Based on read across data from the analogue CAS 422-91-3, the in vitro eye irritation assay provides Insufficient information to classify for eye irritation.
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