4-bromobenzyl alcohol

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-02-08

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= 77.9 - <= 83.7 °C

Atm. press.:

1 013.25 hPa

Decomposition:

no

Sublimation:

no

Appearance of the Samples

Before the test the appearance of the test item was white solid. After the experiments the test item was evaporated from the crucible.

 

Results

The evaluation of the data was performed using the software STARe. As result, a thermogram was obtained in which the heat flow of the investigated sample is given as a function of the temperature. By integrating the area under the heat flow signals, the enthalpy of the process was obtained.

Using a 10 °C/min heating rate, the melting point of the test item was determined to be in the range of 77.9 – 83.7 °C (351.1 – 356.8 K).

Table 1: Values of the DSC run in the first experiment

Sample weight [mg]	Total loss of Mass of the Sample (%)	Onset of effect [°C]	Endset of effect [°C]	Peak Maxium [°C]	Energy [J/g]
6.15	99.8	78.15	83.84	80.47	- 101.44 (endothermic)

Table 2: Values of the DSC run in the second experiment

Sample weight [mg]	Total loss of Mass of the Sample (%)	Onset of effect [°C]	Endset of effect [°C]	Peak Maxium [°C]	Energy [J/g]
8.80	100.0	77.73	83.52	79.32	- 112.89 (endothermic)

Table 3: Summary of the DSC Test of 4-Bromobenzyl alcohol

	Experiment 1	Experiment 2	Mean
Onset of effect [°C]	78.15	77.73	77.94
Endset of effect [°C]	83.84	83.52	83.68

Conclusions:

The melting point of the test item was determined to be in the range of 77.9 and 83.7 °C (351.1 – 356.8 K).

Executive summary:

A study was performed according to OECD TG 102, Commission Regulation (EC) No. 440/2008 method A.1 and OPPTS 830.7200 in order to determine the melting point of the test item by using differential scanning calometry method (DSC). The evaluation of the data was performed using the software STARe. As result, a thermogram was obtained in which the heat flow of the investigated sample is given as a function of the temperature. By integrating the area under the heat flow signals, the enthalpy of the process was obtained. Using a 10 °C/min heating rate, the melting point of the test item was determined to be in the range of 77.9 and 83.7 °C (351.1 - 356.8 K) at 1013.25 hPa.

Description of key information

The melting point of the test item was determined to be in the range of 77.9 and 83.7 °C (351.1 – 356.8 K).

Additional information

A study was performed according to OECD TG 102, Commission Regulation (EC) No. 440/2008 method A.1 and OPPTS 830.7200 in order to determine the melting point of the test item by using differential scanning calometry method (DSC). The evaluation of the data was performed using the software STARe. As result, a thermogram was obtained in which the heat flow of the investigated sample is given as a function of the temperature. By integrating the area under the heat flow signals, the enthalpy of the process was obtained. Using a 10 °C/min heating rate, the melting point of the test item was determined to be in the range of 77.9 and 83.7 °C (351.1 - 356.8 K) at 1013.25 hPa (reference 4.2-1).