Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
GLP compliance:
yes
Type of method:
effusion method: Knudsen cell

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: crystalline
Specific details on test material used for the study:
Batch number: 2015030121

Results and discussion

Vapour pressure
Temp.:
20 °C
Vapour pressure:
0.004 Pa

Any other information on results incl. tables

Results

 

Data in the tables are rounded values taken from Excel spreadsheets which will be archived together with the raw data. The use of Excel spreadsheets for calculations produces more accurate endpoints. These endpoints may slightly differ from the values derived by replacing the rounded values in the formulae given in the methods section.

 

Since the analysis was conducted under high vacuum conditions, the heat could be transferred only by radiation, this caused a consistent difference between the furnace temperature and the sample one and a considerable time for the system to reach equilibrium.

The temperatures reported (registered by the thermocouple under the Knudsen cell) are hence different from the one set and the mass loss has been measured only in 80 minutes time interval within each isotherm, after the system had reached equilibrium.

Table10 Vapour pressure

 

Temperature

[°C]

Dm

[mg]

Dt

[min]

Temperature

[K]

38.8

0.0128

80

311.95

45.2

0.0334

80

318.35

51.6

0.0510

80

324.75

58.5

0.0826

80

331.65

65.7

0.1571

80

338.85

73.1

0.2417

80

346.25

1/Temperature

[1/K]

Dm/Dt

[kg/s]

Vapour pressure

[Pa]

log p

3.21E-03

2.67E-12

1.99E-02

-1.7020

3.14E-03

6.96E-12

5.24E-02

-1.2810

3.08E-03

1.06E-11

8.07E-02

-1.0929

3.02E-03

1.72E-11

1.32E-01

-0.8789

2.95E-03

3.27E-11

2.54E-01

-0.5950

2.89E-03

5.04E-11

3.95E-01

-0.4032

y =mx +q

Parameterm

(slope)

Parameterq

(intercept)

ParameterR2

(correlation)

-3946

11

0.98515

Extrapolation at

20 °C

1/Temperature

[1/K]

log p

Vapour pressure

[Pa]

0.00341

-2.4303

3.71 x10-03

 

Applicant's summary and conclusion

Conclusions:
Vapour Pressure of the substance is 3.71 x 10-3 Pa at 20°C.