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EC number: 226-109-5 | CAS number: 5281-04-9
Subacute study of test chemical was assessed for its possible toxic potential. For this purpose The test chemical was administrated by oral gavage to 20(10 for recovery group) male and female rats by using test concentration of0 and1000 mg/kg/day. The animals were observed for clinical sign, mortality, food consumption, body weight, haematology, clinical chemistry, urine analysis, gross pathology and histopathology. No mortality was observed at treated group 1000 mg/kg/day. Significant effect were observed for body weight and histopatholgy at the dose level of 1000mg/kg bw/day in treated group compare to control. But reversible effect were observed in recovery animals. No significant effect were observed at this dose. Therefore NOAEL was considered to be < 1000mg/kg bw/day for test chemical in male and female rat by oral gavage for subacute study.
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