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Hydrolysis

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Reference
Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Data is from authoritative database and secondary source
Qualifier:
according to
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
Principles of method if other than guideline:
Determination of hydrolysis of test chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate at different pH range. The study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH).
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material (IUPAC name): calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate- Common name: C. I. Pigment 57:1- Molecular formula: C18H12CaN2O6S- Molecular weight: 424.445 g/mol- Smiles notation: c12c(c(c(C(=O)[O-])cc1cccc2)O)\N=N\c1c(cc(C)cc1)S(=O)(=O)[O-].[Ca+2]- InChI: 1S/C18H14N2O6S.Ca/c1-10-6-7-14(15(8-10)27(24,25)26)19-20-16-12-5-3-2-4-11(12)9-13(17(16)21)18(22)23;/h2-9,21H,1H3,(H,22,23)(H,24,25,26);/q;+2/p-2/b20-19+;- Substance type: Organic - Physical state: Solid- Purity: 95-97%
Radiolabelling:
not specified
Analytical monitoring:
not specified
Temp.:
50 °C
Remarks:
Study was performed at different pH range, i.e, at pH 4, 7 and 9.
Positive controls:
not specified
Negative controls:
not specified
Transformation products:
not specified
pH:
4
Temp.:
50 °C
Remarks on result:
other: at pH range 4, 5 and 7, respectively. Half-life value of test chemical is not known, but chemical is stable i.e not hydrolysed at pH 4, 7 and 9, respectively.
Details on results:
Test chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate was reported to be hydrolytically stable at pH 4, 7 and 9, respectively and at a temperature of 50⁰C.
Validity criteria fulfilled:
not specified
Conclusions:
Test chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate was reported to be hydrolytically stable at pH 4, 7 and 9, respectively and at a temperature of 50⁰C.
Executive summary:

The half-life of the test chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate (CAS no. 5281-04-9) was determined at different pH range. The study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH) at a temperature of 50°C. Although, half-life value of test chemical is not known, but chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoatewas reported to be hydrolytically stable at pH 4, 7 and 9, respectively and at a temperature of50⁰C. Based on this, it is concluded that the chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoateisnot hydrolysable.

Description of key information

The half-life of the test chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate (CAS no. 5281-04-9) was determined at different pH range. The study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH) at a temperature of 50°C. Although, half-life value of test chemical is not known, but chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoatewas reported to be hydrolytically stable at pH 4, 7 and 9, respectively and at a temperature of50⁰C. Based on this, it is concluded that the chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoateisnot hydrolysable.

Key value for chemical safety assessment

Additional information

The half-life of the test chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoate (CAS no. 5281-04-9) was determined at different pH range. The study was performed according to OECD Guideline 111 (Hydrolysis as a Function of pH) at a temperature of 50°C. Although, half-life value of test chemical is not known, but chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoatewas reported to be hydrolytically stable at pH 4, 7 and 9, respectively and at a temperature of50⁰C. Based on this, it is concluded that the chemical calcium 3-hydroxy-4-[(4-methyl-2-sulfonatophenyl)diazenyl]-2-naphthoateisnot hydrolysable.