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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
experimental data of read across substances
Justification for type of information:
Data for the target chemical is summarized based on the structurally similar read across chemicals
Reason / purpose for cross-reference:
read-across source
Reason / purpose for cross-reference:
read-across source
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
WoE report is based on three biodegradation studies as- 1. and 2..
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material : Cyperus scariosus, ext.- Common name : Nagarmotha essential oil- Substance type : Organic- Physical state : Liquid
Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Details on inoculum:
- Concentration of sludge: 30 mg/l
Duration of test (contact time):
> 14 - < 28 d
Initial conc.:
100 mg/L
Based on:
test mat.
Remarks:
(1) and (2)
Parameter followed for biodegradation estimation:
TOC removal
Parameter followed for biodegradation estimation:
other: BOD and GC
Details on study design:
1. Standard type2. Improved type for a volatile substance
Parameter:
other: BOD
Value:
> 92 - < 95
Sampling time:
28 d
Remarks on result:
other: Other details not known
Parameter:
other: GC
Value:
100
Sampling time:
28 d
Remarks on result:
other: Other details not known
Parameter:
other: BOD
Value:
73
Sampling time:
14 d
Remarks on result:
other: %degradation = 41-98% (on the upward trend)
Parameter:
% degradation (TOC removal)
Value:
68
Sampling time:
14 d
Remarks on result:
other: *Reference value (calculated based on a theoretical DOC value)
Parameter:
other: GC
Value:
100
Sampling time:
14 d
Remarks on result:
other: Other details not known
Details on results:
1. Test substance undergoes 92-95 and 100% degradation by BOD and GC parameter in 28 days.2. Test substance undergoes 73, 68 and 100% degradation by BOD, TOC removal and GC parameter in 14 days.
Validity criteria fulfilled:
not specified
Interpretation of results:
readily biodegradable
Conclusions:
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the percentage degradation of the test chemical Cyperus scariosus, ext. can be expected to be range from 73-95, 68 and 100, respectively by BOD, TOC removal and GC parameter in 14-28 days. Thus, based on this, test chemical Cyperus scariosus, ext. is considered to be readily biodegradable in nature.
Executive summary:

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the biodegradability of the test chemical Cyperus scariosus, ext.. (CAS no. 91771 -62 -9). The studies are as mentioned below:

Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 92-95 and 100% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in nature.

Another biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of test substance. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 73, 68 and 100% by BOD, TOC removal and GC parameter in 14 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in nature.

On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the percentage degradation of the test chemical Cyperus scariosus, ext. can be expected to be range from 73-95, 68 and 100, respectively by BOD, TOC removal and GC parameter in 14-28 days. Thus, based on this, test chemical Cyperus scariosus, ext. is considered to be readily biodegradable in nature.

Description of key information

On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the percentage degradation of the test chemical Cyperus scariosus, ext. can be expected to be range from 73-95, 68 and 100, respectively by BOD, TOC removal and GC parameter in 14-28 days. Thus, based on this, test chemical Cyperus scariosus, ext. is considered to be readily biodegradable in nature.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the biodegradability of the test chemical Cyperus scariosus, ext. (CAS no. 91771-62-9). The studies are as mentioned below:

 

Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 92-95 and 100% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in nature.

 

Another biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of test substance. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 73, 68 and 100% by BOD, TOC removal and GC parameter in 14 days. Thus, based on percentage degradation, test chemical is considered to be readily biodegradable in nature.

 

On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the percentage degradation of the test chemical Cyperus scariosus, ext. can be expected to be range from 73-95, 68 and 100, respectively by BOD, TOC removal and GC parameter in 14-28 days. Thus, based on this, test chemical Cyperus scariosus, ext. is considered to be readily biodegradable in nature.