Registration Dossier
Registration Dossier
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EC number: 946-756-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
In an in vivo skin irritation test in guinea pig, the test item was applied to depilated skin for 24 h under occlusive conditions. A visual inspection revealed slight irritation of the skin area.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Qualifier:
- no guideline followed
- GLP compliance:
- not specified
- Species:
- guinea pig
- Strain:
- not specified
- Type of coverage:
- occlusive
- Preparation of test site:
- other: depilated
- Vehicle:
- not specified
- Controls:
- not specified
- Duration of treatment / exposure:
- 24 h
- Irritation parameter:
- other: visual inspection
- Basis:
- mean
- Time point:
- 24 h
- Reversibility:
- not specified
- Remarks on result:
- not determinable because of methodological limitations
- Interpretation of results:
- other: No irritation expected under normal exposure conditions. Animals in this test were exposed for 24 hours under an occlusive dressing und only showed slight irritation.
Reference
Additional information
In an in vivo skin irritation test in guinea pig, the test item was applied to depilated skin for 24 h under occlusive conditions. A visual inspection revealed slight irritation of the skin area. No irritation is expected under normal exposure conditions. Animals in this test were exposed for 24 hours under an occlusive dressing und only showed slight irritation.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
