Registration Dossier
Registration Dossier
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EC number: 288-509-6 | CAS number: 85736-97-6
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
- Justification for type of information:
- A study on acute inhalation toxicity is unjustified in accordance to REACH regulation Annex XI due to scientific considerations. Results of laboratory animal studies show a low acute toxicity after oral exposure. Therefore, the acute intrinsic toxic activity of Isotridecyl methacrylate is considered to be low. The occurrence of a systemic toxicity relevant to humans after inhalation is unlikely based on the low vapor pressure of 0.000554 hPa at 20 °C and the use profile. Therefore the conduct of an acute inhalation toxicity study is unjustified, also in respect to animal welfare stated in the REACH intentions.
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
