Registration Dossier
Registration Dossier
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EC number: 700-303-4 | CAS number: 84163-13-3
Oxidising properties
Administrative data
- Endpoint:
- oxidising solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 08 May 2017 - 15 September 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2018
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.17 (Oxidising Properties (Solids))
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: United Nations (UN), UN no. ST/SG/AC.10/11/Rev.6
- Version / remarks:
- United Nations (UN), UN no. ST/SG/AC.10/11/Rev.6: Recommendations on the Transport of Dangerous Goods, Part III: Classification Procedures, Test Methods and Criteria Relating to Class 2, Class 3, Class 4, Division 5.1, Class 8 and Class 9, Test O.1: “Test for Oxidizing Solids”, 2015.
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 6-FLUORO-3-(PIPERIDIN-4-YL)-1,2-BENZOXAZOLE HYDROCHLORIDE
- EC Number:
- 700-303-4
- Cas Number:
- 84163-13-3
- Molecular formula:
- C12H13FN2O.HCl
- IUPAC Name:
- 6-FLUORO-3-(PIPERIDIN-4-YL)-1,2-BENZOXAZOLE HYDROCHLORIDE
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: I16EC2452
- Analytical purity: 100.2% (based on assay; calculated on anhydrous basis)
- Expiration date: 22 November 2020 (retest date)
- Storage condition: at room temperature
Study design
- Contact with:
- other: Potassium bromate
- Duration of test (contact time):
- 64 h
Results and discussion
Test results (Oxidising solids)open allclose all
- Sample tested:
- 1:1 sample-to-cellulose ratio
- Parameter:
- burning rate
- Result:
- > 180 s
- Sample tested:
- 4:1 sample-to-cellulose ratio
- Parameter:
- burning rate
- Result:
- > 180 s
Any other information on results incl. tables
- The mean burning time of both test substance mixtures was more than the mean burning time of the 3:7 (w/w) reference mixture. According to this, the test substance has no oxidizing properties.
-Burning rates of potassium bromate / cellulose mixtures are as follows:
| Potassium bromate/cellulose (w/w) | Burning time [s] | Mean burning time [s] |
| 3:7 | 118 | 113 |
| 114 | ||
| 107 | ||
| 116 | ||
| 111 | ||
| 2:3 | 54 | 53 |
| 55 | ||
| 51 | ||
| 49 | ||
| 53 | ||
| 3:2 | 17 | 16 |
| 16 | ||
| 16 | ||
| 18 | ||
| 15 |
- Burning rates of test substance / cellulose mixtures are as follows:
| Test substance/cellulose (w/w) | Burning time [s] | Mean burning time [s] |
| 4:1 | > 180 | > 180 |
| > 180 | ||
| > 180 | ||
| > 180 | ||
| > 180 | ||
| 1:1 | > 180 | > 180 |
| > 180 | ||
| > 180 | ||
| > 180 | ||
| > 180 |
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The full test was performed to monitor the oxidizing properties of JNJ-1782820-AAC (T001492).
Based on the results obtained it was concluded that the test substance has no oxidizing properties and is therefore not classified as a Division 5.1 substance.
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