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Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Qualifier:
according to
Guideline:
other: Directive CEE - Méthode B1 ter et OCDE 423.
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes
Specific details on test material used for the study:
Lot DSC-9401
Species:
other: Rat, Sprague-Dawley
Vehicle:
other: Purified water
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Female: 2000 mg/kg bw; Number of animals: 6; Number of deaths: 0
Clinical signs:
Signs of toxicity related to dose levels : no clinical sign and no mortality were observed during the study


L'évolution pondérale des animaux n'est pas influencée par
le traitement avec la substance.
Gross pathology:
Effects on organs: no apparent anomalies are observed during the macroscopic examination of the main organs of sacrificed animals at the end of the study
Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
10 000 mg/kg bw

Additional information

Justification for classification or non-classification