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There is no biodegradation information available for 3,6,9,12-tetraoxatetradecan-1-ol. However, the closely related read across substance 2 -(2 -(2 -ethoxyethoxy)ethoxy)ethanol was found to be readily biodegradable in a guideline study in freshwater where the BOD28 was 92.1%. The biodegradation was also assessed at a number of concentrations using a non-adapted domestic sewage innoculum in a freshwater medium. Ready degradation was observed with a BOD20 of 71%. In a single study in saltwater using the same substance, evidence of biodegradation was seen with 22% degradation after 20 days. A reliable QSAR predicts that 3,6,9,12-tetraoxatetradecan-1-ol will be readily biodegradable. The available data leads to a reliable conclusion that 3,6,9,12-tetraoxatetradecan-1-ol will be readily biodegradable