Registration Dossier
Registration Dossier
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EC number: 203-319-5 | CAS number: 105-65-7
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The results are based on AS100 data (the polysulphide structural equivalent but as it hydrolyses to DIXD it is scientifically justifiable to read-across the results for DIXD. The effect of the test material on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 of greater than 1000 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 1000 mg/l.
Key value for chemical safety assessment
- EC50 for microorganisms:
- 1 000 mg/L
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
Introduction.
A study was performed to assess the effect of the test material on the respiration of activated sewage sludge. The method followed that described in the OECD Guidelines for Testing of Chemicals (1984) No 209 "Activated Sludge, Respiration Inhibition Test", EEC Commission Directive 87/302/EEC and US EPA Draft Ecological Effects Test Guidelines OPPTS 850.6800.
Methods.
Following preliminary range-finding tests, activated sewage sludge was exposed to an aqueous dispersion of the test material at a concentration of 1000 mg/l (three replicate flasks) for a period of 3 hours at a temperature of 21°C with the addition of a synthetic sewage as a respiratory substrate.
The rate of respiration was determined after 30 minutes and 3 hours contact time and compared to data for the control and a reference material, 3,5-dichlorophenol.
Results.
The effect of the test material on the respiration of activated sewage sludge gave a 3‑Hour EC50of greater than 1000 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 1000 mg/l.
The reference material gave a 3-Hour EC50value of 13 mg/l.
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