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EC number: 204-145-2 | CAS number: 116-53-0
2-methylbutyric acid is readily biodegradable: 68% biodegradation within 10 days (similar to OECD 301D, Dias and Alexander 1971).
A reliable key study is available (RL2). The biodegradability of 2-methylbutyric acid and numerous related substances (aliphatic acids and alcohols) was determined in a pre-guideline study. Reporting is limited but the test procedure follows in general the method of OECD TG 301 D (Closed Bottle Test). After 10 days, 2-methylbutyric acid was degraded to ca. 68% (day 5: ca. 65%) (calculated from the originally reported data of oxygen consumption). Based on the oxygen consumption data, 2-methylbutyric acid is readily biodegradable (Dias and Alexander, 1971).
In a supporting study, 2 -Methylbutyric acid was tested for biodegradability in a pre-guideline test following the original method of Zahn-Wellens. Test method is reported with no specific details, but the general procedure is comparable to OECD test guideline 302 B (Zahn-Wellens/EMPA Test). After 10 days 2-methylbutyric acid was biodegraded by >95% (Hoechst, 1980).
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