Registration Dossier
Registration Dossier
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EC number: 264-867-9 | CAS number: 64396-12-9
Endpoint summary
Administrative data
Description of key information
Succinic acid and salts are found naturally in cells as metabolites and low molecular weight / water soluble derivatives have been evaluated for use in foods and cosmetics and concluded to be of low toxicity. There is no evidence of any target organ effect at treatment levels regarded as reasonable for assessment (ie up to 1000 mg/kg/day).
Triethanolamine has been extensively assessed for toxic effects in view of the widespread use of the amine and derivatives in cosmetic ingredients.
Based on the assessment for the dissociation products, there is no indication that there will be adverse effect on health, including target organ effects or effects on reproduction.
Further animal testing cannot be justified on this salt.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
