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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference Type:
study report

Materials and methods

Test guideline
according to guideline
OECD Guideline 203 (Fish, Acute Toxicity Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
EC Number:
EC Name:
Cas Number:
Molecular formula:
2-aminoethanesulfonic acid
Specific details on test material used for the study:
CAS-No.: 107-35-7
Batch No.: XP19124394
Purity: 99.4 % (assay on the dried basis) according to certificate of analysis
Certificate of Analysis Date: December 31, 2019
Aggregate State at Room Temperature: Solid
Colour: White
Expiry Date: December 25, 2022
Storage Conditions at Test Facility: At 20 ± 5 °C, in the dark

Test solutions


Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Details on test organisms:
- Common name: Rainbow trout (Oncorhynchus mykiss)
- Source: The test fish were obtained from Forellenzuchtbetrieb Störk, 88348 Bad Saulgau, Germany
- Age at study initiation (mean and range, SD): Juveniles
- Length at study initiation (length definition, mean, range and SD):
- Weight at study initiation (mean and range, SD): The mean body length of the fish* in the test was 4.20 cm ± 0.2 cm (Mean ± SD), the mean body wet weight 0.72 g ± 0.1 g (Mean ± SD)

- Acclimation period: All fish were obtained and held in the laboratory for at least 9 days before the start of the test.
- Acclimation conditions (same as test or not): They were held in water of the quality to be used in the test for at least seven days immediately before testing under the following conditions:
Light: 12 hours photoperiod daily
Temperature: 10 - 14 °C
Oxygen concentration: at least 80 % of the air saturation value
Feeding: three times per week or daily until 24 hours before the test was started
During the last 7 days prior to the start of the test no fish (0 %) died in the test fish batch. Therefore the mortalities in the fish batch were below 5 % and the fish batch was accepted.

Light Regime: 12 h light : 12 h dark; 30 min dawn/dusk period was provided
Light Intensity: 550 to 610 lux

Study design

Test type:
Water media type:
Limit test:
Total exposure duration:
96 h

Test conditions

40 – 250 mg/L CaCO3, preferably < 180 mg/L CaCO3
Test temperature:
12.8 to 13.9 °C
7.2 to 8.1
Dissolved oxygen:
95 to 101 % of the air saturation value
Nominal and measured concentrations:
100 mg test item/L (spacing factor 2.2) and a control.

Results and discussion

Effect concentrationsopen allclose all
Key result
96 h
Dose descriptor:
Effect conc.:
> 100 mg/L
Nominal / measured:
Conc. based on:
test mat.
Key result
96 h
Dose descriptor:
Effect conc.:
> 100 mg/L
Nominal / measured:
Conc. based on:
test mat.

Applicant's summary and conclusion

Validity criteria fulfilled:
The toxic effect of the test item Taurine to Rainbow Trout (Oncorhynchus mykiss) was assessed in a semi-static limit test. Based on the test results the 96-hour LC50 was determined to be > 100 mg test item/L based on nominal concentrations. The NOEC was determined to be ≥ 100 mg test item/L also based on nominal concentrations.
The initial concentrations and the maintenance of the exposure concentrations during the test were verified in the analytical part. All reported results refer to nominal values since the concentrations of the test item were within ± 20 % of the nominal concentrations during the test.
Executive summary:

In the control and the only test concentration of 100 mg test item/L, all fish survived until the end of the experiment and showed no sublethal effects during the exposure time.

The LC50 could not be quantified due to the absence of toxicity of the test item. The NOEC and the LOEC were determined directly from the raw data.