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EC number: 602-941-8 | CAS number: 123560-48-5
The purpose of this study was to determine the bioconcentration potential of the test material in fish under flow-through conditions. During the GLP compliant test the lethal and other effects in fish were determined during the exposure period of 28 days.
The study was performed according to the OECD Guideline for Testing of Chemicals 305 (Bioconcentration: Flow-through Fish Test) adopted on June 14, 1996 using two test material concentrations for exposure to Cyprinus carpio. Two environmental concentrations of the test material of 0.02 and 0.002 mg/L were used in this study. The exposure was concentration was maintained using SPAN 20 as solubiliser. The concentrations were verified analytically using a HPLC method with UV detection.
There were no mortality and no signs of toxicity detected throughout the study in any dose group up to 28 days of exposure.
The test material showed no relevant toxic potential at concentrations above the limit of water solubility.
NOEC (BCF, 28d) >= 0.02 mg/L (with SPAN 20 as solubiliser)
For this endpoint data from a long term (28 d) bioconcentration study provide adequate information. This study has used SPAN 20 as vehicle to increase water solubility. In the long term 28 days study no mortality was observed up to 0.02 mg/L. Therefore, the test material does not exhibit a significant potential for toxicity up the limit of water solubility.
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