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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic plants other than algae

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic plants other than algae
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
30 July 2002 - 9 August 2002
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
Study only partially conducted. Experimental work was conducted under GLP conditions and in accordance with generally accepted scientific principles but with incomplete reporting. The study was terminated early and few experimental details are included in the report. It is therefore not possible to assess the reliability of the data.
Qualifier:
according to guideline
Guideline:
OECD Guideline 221 (Lemna sp. Growth Inhibition Test)
Deviations:
yes
Remarks:
- see below
Qualifier:
according to guideline
Guideline:
other: FIFRA Guideline 122-2
Deviations:
yes
Remarks:
- see blelow
Qualifier:
according to guideline
Guideline:
other: FIFRA Guideline 123-2
Deviations:
yes
Remarks:
- see below
Principles of method if other than guideline:
The preliminary range-finding test was terminated on Day 10 of the study per the request of the sponsor.
GLP compliance:
yes
Test organisms (species):
Lemna gibba
Test type:
not specified
Water media type:
not specified
Limit test:
no
Total exposure duration:
10 d
Nominal and measured concentrations:
- Nominal concentrations: 0.0010, 0.010, 0.10 and 1.0 mg a.i./L
Details on results:
The mean frond densities after 10 days are presented in Table 1.

Table 1: Mean Frond Densities After 10 Days

Nominal Conc.

(mg a.i./L)

Replicate

Mean

A

B

Solvent

455

448

452

Solvent Control

414

524

469

0.0010

419

389

404

0.010

459

436

448

0.10

444

440

442

1.0

463

428

446
Validity criteria fulfilled:
not applicable
Conclusions:
The preliminary range-finding test was terminated on Day 10 of the study per the request of the sponsor.
Executive summary:

A study was initiated to assess the toxicity of the test material to Lemna gibba in accordance with the standardised guidelines OECD 221 and US EPA FIFRA guidelines 122-2 and 123-2 under GLP conditions.

In a preliminary study, Lemna gibba was exposed to the test material at concentrations of 0.0010, 0.010, 0.10 and 1.0 mg a.i./L, along with a control and solvent control.

At the request of the study sponsor, the preliminary range-finding test was terminated on Day 10 of the study.

Description of key information

The preliminary range-finding test was terminated on Day 10.

Key value for chemical safety assessment

Additional information

A study was initiated to assess the toxicity of the test material to Lemna gibba in accordance with the standardised guidelines OECD 221 and US EPA FIFRA guidelines 122-2 and 123-2 under GLP conditions.

In a preliminary study, Lemna gibba was exposed to the test material at concentrations of 0.0010, 0.010, 0.10 and 1.0 mg a.i./L, along with a control and solvent control.

The preliminary range-finding test was terminated on Day 10 of the study per the request of the sponsor. Therefore the study was awarded a reliability score of 4 in accordance with the criteria set forth by Klimisch et al. (1997).