Registration Dossier
Registration Dossier
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EC number: 210-194-0 | CAS number: 609-65-4
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- publication
- Title:
- Bioaccumulation of 2-chlorobenzoic acid
- Year:
- 1 971
- Bibliographic source:
- J-Check Database last access 29.03.2018. Study conducted and owned by the Japanese Government (Ministry of Health, Labour and Welfare, Ministry of Economy, Trade and Industry, and Ministry of the Environment).
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: "Bioaccumulation test of a chemical substance in fish or shellfish" provided in "the Notice on the Test Method Concerning New Chemical Substances"
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-chlorobenzoic acid
- EC Number:
- 204-285-4
- EC Name:
- 2-chlorobenzoic acid
- Cas Number:
- 118-91-2
- Molecular formula:
- C7H5ClO2
- IUPAC Name:
- 2-chlorobenzoic acid
Constituent 1
- Specific details on test material used for the study:
- Purity 99 %
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Cyprinus carpio
Study design
- Total depuration duration:
- 6 wk
Test conditions
- Details on test conditions:
- RANGE-FINDING / PRELIMINARY STUDY - Test concentrations : TLm(48h) 255 ppm(w/v), Rice fish (Oryzias latipes)
Results and discussion
Bioaccumulation factoropen allclose all
- Conc. / dose:
- 0.125 other: ppm
- Type:
- BCF
- Value:
- <= 10 L/kg
- Basis:
- whole body w.w.
- Conc. / dose:
- 1.25 other: ppm
- Type:
- BCF
- Value:
- <= 1 L/kg
- Basis:
- whole body w.w.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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